发明名称 |
7-substituted camptothecin and camptothecin analogs and methods for producing the same |
摘要 |
Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex.
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申请公布号 |
US7067666(B2) |
申请公布日期 |
2006.06.27 |
申请号 |
US20030606795 |
申请日期 |
2003.06.27 |
申请人 |
RESEARCH TRIANGLE INSTITUTE |
发明人 |
WANI MANSUKH C.;MANIKUMAR GOVINDARAJAN;WALL MICHAEL A. |
分类号 |
C07D515/22;A61K31/357;A61K31/436;C07D491/22 |
主分类号 |
C07D515/22 |
代理机构 |
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地址 |
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