发明名称 |
3-AMINOMETHYL-PYRROLIDINES AS N-TYPE CALCIUM CHANNEL BLOCKERS. |
摘要 |
<p>The invention relates to compounds that are derivatives of 3-aminomethyl-pyrrolidine of the formulas: wherein: Y is (X2)1A or (X1)mCR4A2; W is CR4 or N; R1-R4 are noninterfering substituents; n is 0-7; 1 and m are independently 0 or 1; X1-X2 are linkers; each A is independently a 5-7 membered optionally substitued aromatic or aliphatic ring optionally containing one or more heteroatoms selected from O, N and S. They generally contain at least one benzhydril moiety and are useful in treating conditions which benefit from blocking calcium ion channels.</p> |
申请公布号 |
MXPA05012899(A) |
申请公布日期 |
2006.06.23 |
申请号 |
MX2005PA12899 |
申请日期 |
2004.05.28 |
申请人 |
NEUROMED TECHNOLOGIES, INC. |
发明人 |
YANBING DING |
分类号 |
A61K31/40;A61K31/4025;A61K31/454;A61K31/496;A61K31/5377;A61K31/541;A61P9/00;A61P25/00;C07D207/09;C07D413/02;C07D417/02;(IPC1-7):A61K31/40 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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