| 摘要 |
Extracts of various species of the family Berberidaceae have estrogenic properties. For example, aqueous and ethanolic extracts of Epimedium species possess estrogenic properties in both ERalpha+ and ERbeta+ cells. These estrogenic effect include estrogen response element (ERE) stimulation as well as tumor necrosis factor (TNF) repression. Methods are provided for treating climacteric symptoms, breast and/or uterine cancer, and osteoporosis.
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