Mucoadhesive composition and formulation for solubilization of insoluble drugs and preparation method thereof

摘要

The present invention relates to a novel mucoadhesive composition for solubilization of insoluble drugs; its formulation including pharmaceutical compounds; and the preparation methods thereof wherein said solubilizing composition comprises 4~90% by weight of at least one selected from the monoglycerides and 0.01~90% by weight of at least one oil. The present invention relates to a novel mucoadhesive composition including pharmaceutical compounds; and the preparation methods thereof wherein said solubilizing composition including emulsifiers is composed of 4~90% by weight of at least one selected from the monoglycerides, 0.01~90% by weight, of at least one oil, and 0.01~90% by weight of at least one selected from the emulsifiers. The compositions of the present invention is suitable as drug delivery systems since they exist as mucoadhesive liquid at physiological temperatures even though they exist as liquid or semi-solid at room temperature.