发明名称 |
PROCESS AND INTERMEDIATE COMPOUNDS USEFUL IN THE PREPARATION OF STATINS |
摘要 |
<p>There is provides a process for the preparation of a compound of formula (7): wherein R is an optionally substituted hydrocarbyl group or an optionally substituted heterocyclic group; provides that R is not a compound of Formula (a): wherein R<SUP>a</SUP> represents an alkyl group, such as a C<SUB>1-16</SUB> alkyl group, and preferably an isopropyl group; R<SUP>b</SUP> represents an aryl group, preferably a 4-fluorophenyl group; R<SUP>c</SUP> represents hydrogen, a protecting group or an alkyl group, such as a C<SUB>1-16</SUB> alkyl group, and preferably a methyl group; and Rd represents hydrogen, a protecting group or a SO<SUB>2</SUB>R<SUP>e</SUP> group where R<SUP>e</SUP> is an alkyl group, such as a C<SUB>1</SUB>-<SUB>16</SUB> alkyl group, and preferably a methyl group.</p> |
申请公布号 |
WO2006064179(A1) |
申请公布日期 |
2006.06.22 |
申请号 |
WO2005GB04541 |
申请日期 |
2005.11.28 |
申请人 |
AVECIA PHARMACEUTICALS LIMITED;MOODY, DAVID, JOHN;WIFFEN, JONATHAN, WILLIAM |
发明人 |
MOODY, DAVID, JOHN;WIFFEN, JONATHAN, WILLIAM |
分类号 |
C07C51/09;C07C61/29;C07C67/28;C07C69/30;C07D209/12;C07D209/18;C07D215/14;C07D257/04;C07D309/10;C07D405/06 |
主分类号 |
C07C51/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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