A hydrophilic semipermeable membrane can include a porous polymeric structure containing a blend of PVDF and hydroxyalkylcellulose. The membrane may be used for ultrafiltration. A method of making a hydrophilic semipermeable membrane can include providing a blend containing PVDF and hvdroxyalkylcellulose. forming the hlernd into a porous polymeric structure, and purifying the porous polymeric structure. Figure 4 is a SFM image oha cross-section of a hydrophilic membrane.