发明名称 NOVEL POLYPEPTIDE AND NUCLEIC ACID ENCODING THE SAME
摘要 PROBLEM TO BE SOLVED: To provide identification and isolation of a novel DNA, recombinant production of a novel polypeptide encoded by the DNA, and application of the polypeptide. SOLUTION: A specific nucleic acid sequence encoding a polypeptide with a specific amino acid sequence (polypeptide having homology with extremely long-chain acyl-CoA synthetase) which is newly isolated, a vector comprising the nucleic acid sequence, a host cell expressing the vector, a chimeric polypeptide molecule comprising the polypeptide fused to a heterologous polypeptide sequence such as an immunoglobulin, and an antibody which binds to the polypeptide, are provided. They are available for treatment and diagnosis of cancer. COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006160750(A) 申请公布日期 2006.06.22
申请号 JP20060011809 申请日期 2006.01.20
申请人 GENENTECH INC 发明人 WOOD WILLIAM I;GODDARD AUDREY;GURNEY AUSTIN;YUAN JEAN;BAKER KEVIN P;CHEN JIAN
分类号 C07K14/82;C12N15/09;A61K31/7088;A61K35/76;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P7/02;A61P9/00;A61P19/08;A61P25/02;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P35/00;A61P43/00;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C07K16/30;C07K16/32;C07K16/40;C07K16/46;C07K19/00;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/04;C12N9/64;C12N15/63;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;C12R1/19;C12R1/91;G01N33/50;G01N33/53;G01N33/566;G01N33/68 主分类号 C07K14/82
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