| 摘要 |
Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R, 3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H-1,2,4-triazole-1-yl)butan-2-ol. |
| 申请人 |
DR. REDDY'S LABORATORIES LTD.;DR. REDDY'S LABORATORIES, INC.;SUNDARAM, VENKATARAMAN;UPPALA, VENKATA BHASKARA RAO;AKUNDI, SURYA PRABHAKAR;MUVVA, VENKATESWARLU;CHITTA, VIJAYAWARDHAN;DONTHULA, ALEKHYA;KHARKAR, MANOJ RAMESH;DEVARAKONDA, SURYA NARAYANA;PEDDIREDDY, SUBBA REDDY |
发明人 |
SUNDARAM, VENKATARAMAN;UPPALA, VENKATA BHASKARA RAO;AKUNDI, SURYA PRABHAKAR;MUVVA, VENKATESWARLU;CHITTA, VIJAYAWARDHAN;DONTHULA, ALEKHYA;KHARKAR, MANOJ RAMESH;DEVARAKONDA, SURYA NARAYANA;PEDDIREDDY, SUBBA REDDY |
