INDOLOMORPHINAN DERIVATIVE HAVING CARBOXY IN 6'-POSITION

摘要

A novel compound useful as a therapeutic and/or preventive agent for nausea and/or vomiting. It is a compound represented by the formula (I): (wherein R<SUP>1</SUP> is hydrogen or -CHR<SUP>A</SUP>R<SUP>B</SUP> (wherein R<SUP>A</SUP> is lower alkoxycarbonyloxy, etc. and R<SUP>B</SUP> is hydrogen or methyl)), a pharmaceutically acceptable salt thereof, or a solvate of either.