| 摘要 |
Oxygenating agents are used in the present invention for the novel purpose of treating microbial infections. The invention takes advantage of the fact that the increase in tissue pO<SUB>2 </SUB>produced thereby can enhance the efficacy of the body's own antimicrobial defenses (including tissue repair), while also improving the efficacy of adjunctive agents that may be co-administered, such as antimicrobial agents, antioxidants, cytokine modulators, endotoxin antagonists and growth factors. The oxygenating agents of the present invention achieve the desired increased pO<SUB>2 </SUB>in the tissues without having to resort to the risks and expenses of hyper-baric oxygen therapy (HBO). The oxygenating agents can be administered systemically, regionally, or topically.
|
