Methods for altering levels of phenolic compounds in plant cells

摘要

The present invention provides a plant derived extract comprising inhibitory activity against HIV integrase, wherein the amount of inhibitory activity in an extract can be increased by stressing the plant prior to forming an extract. Furthermore, methods and materials for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are described. In addition, methods for the isolation of enzymes and their encoding genes, which are involved in the biosynthesis of selected phenolic compounds such as depsides are provided as well as transgenic organisms transformed therewith.