Process for preparing pyrrole derivatives and intermediates
摘要
The present invention relates to a process for preparing pyrrole derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, and more particularly to improved synthetic methods for preparing 3,5-dihydroxy-7-pyrrol-1-yl heptanoic acids from 1,4-diketo starting materials. The invention further relates to intermediates in this process:
申请公布号
EP1671947(A1)
申请公布日期
2006.06.21
申请号
EP20040030159
申请日期
2004.12.20
申请人
RATIOPHARM GMBH
发明人
BOBAL, PAVEL;FRANTISEK, JAROSLAV;STOHANDL, JIRI;DENIKE, KANE;BOERNER, ARMIN;TARAROV, VITALI;KOROSTYLEV, ANDREI;KOENIG, GERD;JEKER, NICOLAS