发明名称 AMIDOMETHYL SUBSTITUTED 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS
摘要 Described are novel compounds with neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity of the general formula (I), wherein the substituents R<1>, R<2> , R<3> and R<4> have the meanings given in the description and also medicaments containing these compounds, in particular medicaments suitable for treating or preventing cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis.
申请公布号 EP1670814(A1) 申请公布日期 2006.06.21
申请号 EP20040766846 申请日期 2004.09.23
申请人 SOLVAY PHARMACEUTICALS GMBH 发明人 HOELTJE, DAGMAR;FISCHER, YVAN;ZIEGLER, DIETER;WESKE, MICHAEL;MICHAELIS, KATHRIN;KARIMI-NEJAD, YASMIN;MESSINGER, JOSEF;PAHL, AXEL;HOEFER, CONSTANZE;IKONOMIDOU, HRISSANTHI;TURSKI, LECHOSLAW
分类号 A61K38/00;A61P9/12;C07K5/02;C07K5/078 主分类号 A61K38/00
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