发明名称 |
AMIDOMETHYL SUBSTITUTED 1-(CARBOXYALKYL)-CYCLOPENTYLCARBONYLAMINO-BENZAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS |
摘要 |
Described are novel compounds with neutral endopeptidase (NEP) and/or human soluble endopeptidase (hSEP) inhibitory activity of the general formula (I), wherein the substituents R<1>, R<2> , R<3> and R<4> have the meanings given in the description and also medicaments containing these compounds, in particular medicaments suitable for treating or preventing cardiovascular diseases, sexual dysfunction and/or adverse conditions associated with apoptosis. |
申请公布号 |
EP1670814(A1) |
申请公布日期 |
2006.06.21 |
申请号 |
EP20040766846 |
申请日期 |
2004.09.23 |
申请人 |
SOLVAY PHARMACEUTICALS GMBH |
发明人 |
HOELTJE, DAGMAR;FISCHER, YVAN;ZIEGLER, DIETER;WESKE, MICHAEL;MICHAELIS, KATHRIN;KARIMI-NEJAD, YASMIN;MESSINGER, JOSEF;PAHL, AXEL;HOEFER, CONSTANZE;IKONOMIDOU, HRISSANTHI;TURSKI, LECHOSLAW |
分类号 |
A61K38/00;A61P9/12;C07K5/02;C07K5/078 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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