发明名称 |
PEPTIDE FRAGMENT OF THE RESPIRATORY SYNCYTIAL VIRUS G PROTEIN, IMMUNOGENIC AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PREPARATION METHOD |
摘要 |
<p>New polypeptides (I) useful as immunogenic elements comprise a peptide sequence between amino acids 130 and 230 of the protein G sequence of respiratory syncytial virus (RSV) subgroup A or B, or a sequence having at least 80% homology with this sequence. Also claimed are: (1) an immunogenic agent comprising a polypeptide (I) coupled to a carrier protein; (2) a compsn. for preventing and/or treating RSV subgroup A and/or B infections contg. a polypeptide (I) or an immunogenic agent as in (1); (3) a nucleotide sequence coding for a polypeptide (I); (4) a protein (namely Klebsiella pneumoniae p40 protein) with a defined sequence of 335 amino acids given in the specification, or with 80% homology with this sequence; (5) a nucleotide sequence coding for K.pneumoniae p40 protein; and (6) a process for preparing a peptide conjugate for use in the compsn. of (2).</p> |
申请公布号 |
EP0754231(B1) |
申请公布日期 |
2006.06.21 |
申请号 |
EP19950916721 |
申请日期 |
1995.04.06 |
申请人 |
PIERRE FABRE MEDICAMENT |
发明人 |
BINZ, HANS;N'GUYEN, NGOC, THIEN;BAUSSANT, THIERRY;TRUDEL, MICHEL |
分类号 |
C12N15/09;C12N15/45;A61K38/00;A61K39/155;A61K47/48;A61P31/12;C07H21/04;C07K14/08;C07K14/115;C07K14/135;C07K14/26;C07K14/705;C07K14/765;C07K19/00;C12N15/31;C12P21/02;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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