发明名称 Method of verifying the synthesis of organic molecules using nuclear magnetic resonance spectroscopy
摘要 A NMR method to verify the presence of organic molecular compounds consisting of repetitive occurring individual structures is presented. The method comprises the steps of assigning structure codes to the selected compounds, in accordance with the respective starting compounds used, measuring multi-dimensional NMR spectra from at least some of the compounds, uniquely assigning signal groups of NMR spectra to the individual structures, checking the NMR spectra of the compounds for the presence of all assigned signal groups, and characterizing a particular compound as being TRUE if the check of its particular combination of structures yields the result that the signal groups of structures contained in its total code had been observed. The method permits rapid and accurate verification of the presence of compounds having repetitive structures such as those produced in combinatorial chemistry.
申请公布号 US7064543(B2) 申请公布日期 2006.06.20
申请号 US20030639436 申请日期 2003.08.13
申请人 BRUKER BIOSPIN GMBH 发明人 SCHROEDER HARALD;NEIDIG KLAUS-PETER
分类号 G01V3/00;C07B61/00;G01R33/46 主分类号 G01V3/00
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