发明名称 |
Human voltage gated sodium channel beta1A subunit and methods of use |
摘要 |
DNAs encoding human voltage gated sodium channel beta1A subunit have been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
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申请公布号 |
US7063953(B2) |
申请公布日期 |
2006.06.20 |
申请号 |
US20030401916 |
申请日期 |
2003.03.28 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
QIN NING;CODD ELLEN;D'ANDREA MICHAEL |
分类号 |
C12N15/09;G01N33/567;A61K45/00;A61P9/06;A61P21/02;A61P23/02;A61P25/02;A61P25/08;C07K14/47;C07K14/705;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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