| 发明名称 |
SULFONAMIDE DERIVATIVES |
| 摘要 |
The present invention is directed to sulfonamide derivatives of the general formula (I): (see formula I) wherein R is C6-14 aryl or a heterocyclic residue each of which may have one or more substituents or the salt thereof. The sulfonamide derivatives show strong inhibitory activity against cysteine protease such as calpain papain, cathepsin B, cathepsin H, cathepsin L. They can be used as remedies for muscular dystrophy, cataract, myocardial infarction, stroke, amyotrophia, osteoporosis, hypercalcemia or the like.
|
| 申请公布号 |
CA2121523(C) |
申请公布日期 |
2006.06.20 |
| 申请号 |
CA19942121523 |
申请日期 |
1994.04.18 |
| 申请人 |
ANDO, RYOICHI;SAKAKI, TOSHIRO;TAKAHASHI, CHIZUKO;FUJIMURA, YOSHIYUKI |
发明人 |
ANDO, RYOICHI;SAKAKI, TOSHIRO;TAKAHASHI, CHIZUKO;FUJIMURA, YOSHIYUKI |
| 分类号 |
A61K31/195;C07C311/00;A61K31/18;A61K31/198;A61K31/33;A61K31/44;A61K31/4406;A61P3/14;A61P9/00;A61P9/08;A61P9/10;A61P19/10;A61P21/04;A61P25/28;A61P27/02;A61P27/12;A61P43/00;C07C311/19;C07D207/34;C07D209/48;C07D213/71;C07D215/36;C07D217/22;C07D233/02;C07D233/42;C07D233/84;C07D237/18;C07D237/34;C07D239/38;C07D249/12;C07D257/04;C07D307/64;C07D307/82;C07D309/28;C07D311/58;C07D311/76;C07D333/10;C07D333/34;C07D403/12;C07D473/00;C07D475/00;C07K5/06;C12N9/99 |
主分类号 |
A61K31/195 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
