发明名称 Modular targeted liposomal delivery system
摘要 A liposome including a fusogenic liposome, a linking moiety and a targeting moiety. The fusogenic liposome is a lipid bilayer encapsulating contents. The linking moiety is electrostatically bound to the lipid bilayer, and the targeting moiety is covalently bound to the linking moiety. The liposome may also include a stabilizing moiety interposed between the linking and targeting moieties, and covalently bound to both. Alternatively, the stabilizing and targeting moieties may be covalently bound to separate linking moieties, the linking moieties being electrostatically bound to the lipid bilayer.
申请公布号 US7060291(B1) 申请公布日期 2006.06.13
申请号 US20020130951 申请日期 2002.05.24
申请人 TRANSAVE, INC. 发明人 MEERS PAUL R.;SHANGGUAN TONG;CABRAL-LILLY DONNA;AHL PATRICK;ERUKULLA RAVI;JANOFF ANDREW
分类号 A61K9/127 主分类号 A61K9/127
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