| 发明名称 |
Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas |
| 摘要 |
Process for the preparation of stable activated derivatives of carbamic acid, comprising at least one protected amino group and an activated carbamic acid function, from an amino acid derivative in which the amino group is protected. The process includes: a) a step of transformation of the -COOH group of the amino acid derivative into a -CON<SUB>3 </SUB>group to obtain an acyl azide; b) a step of transformation of the -CON<SUB>3 </SUB>group of the acyl azide into a -NCO group to obtain an isocyanate; c) a step of treating the isocyanate to obtain a stable derivative of carbamic acid.
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| 申请公布号 |
US7060845(B2) |
申请公布日期 |
2006.06.13 |
| 申请号 |
US20010904459 |
申请日期 |
2001.07.16 |
| 申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
GUICHARD GILLES;GALAS-RODRIGUEZ, LEGAL REPRESENTATIVE MARIE-CHRISTINE;RODRIGUEZ, LEGAL REPRESENTATIVE PIERRE;RODRIGUEZ, LEGAL REPRESENTATIVE ELISA;RODRIGUEZ, LEGAL REPRESENTATIVE ROMAIN;SEMETEY VINCENT;BRIAND JEAN-PAUL |
| 分类号 |
C07D207/00;C07D401/12;A61K31/395;A61K31/40;A61K31/4439;A61K31/4725;A61P31/18;A61P37/02;A61P43/00;C07C263/12;C07C265/04;C07C265/12;C07C273/18;C07C275/14;C07C275/16;C07C275/28;C07D207/40;C07D207/404;C07D207/46;C07D259/00;C07D403/12;C08G71/02 |
主分类号 |
C07D207/00 |
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