发明名称 |
Inhibitors of IMPDH enzyme |
摘要 |
The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5'-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as transplant rejection and autoimmune diseases.
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申请公布号 |
US7060720(B2) |
申请公布日期 |
2006.06.13 |
申请号 |
US20030717287 |
申请日期 |
2003.11.19 |
申请人 |
BRISTOL-MYERS SQUIBB CO. |
发明人 |
GU HENRY H.;DHAR T. G. MURALI;IWANOWICZ EDWIN J. |
分类号 |
A61K31/421;A61K31/422;A61K31/427;A61K31/4439;A61K31/4709;A61K31/5377;A61K45/00;A61P29/00;A61P31/12;A61P35/00;A61P37/02;A61P43/00;C07D263/32;C07D307/20;C07D413/12;C07D413/14;C07D417/12;C07D471/04 |
主分类号 |
A61K31/421 |
代理机构 |
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地址 |
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