| 发明名称 |
METHOD OF MANUFACTURE OF 1,3-OXATHIOLANE NUCLEOSIDES |
| 摘要 |
Processes for the preparation of 1,3-oxathiolane nucleosides are provided that include efficient methods for the preparation of the 1,3-oxathiolane ring and subsequent condensation of the 1,3-oxathiolane with a pyrimidine or purine base. Using the processes described herein, the compounds can be provided as isolated enantiomers.
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| 申请公布号 |
KR20060063991(A) |
申请公布日期 |
2006.06.12 |
| 申请号 |
KR20067007631 |
申请日期 |
2006.04.20 |
| 申请人 |
GILEAD SCIENCES, INC.;ALMOND MERRICK;CLEARY DARRYL;SORIA JOSE;SZNAIDMAN MARCOS LUIS;EMORY UNIVERSITY;PAINTER GEORGE R.;LIOTTA DENNIS C. |
发明人 |
PAINTER GEORGE R.;LIOTTA DENNIS C.;ALMOND MERRICK;CLEARY DARRYL;SORIA JOSE;SZNAIDMAN MARCOS LUIS |
| 分类号 |
C07D317/34;A61K31/505;C07D317/24;C07D319/06;C07D327/04;C07D411/04;C07D473/00 |
主分类号 |
C07D317/34 |
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