Production of heterologous proteins in Caulobacter

摘要

The present invention has identified the Caulobacter RsaFa and RsaFb proteins as the OMP components of the S-layer protein secretion machinery. The present invention has also identified that an enhanced production of a heterologous protein from Caulobacter can be achieved by increased production of RsaFa and/or RsaFb. Expression vectors, genetically engineered Caulobacter strains, as well as methods are provided that are useful for producing a heterologous protein in Caulobacter.