发明名称 |
ELECTROPORATION OF MYCOBACTERIUM AND OVEREXPRESSION OF ANTIGENS IN MYCOBACTERIA |
摘要 |
Recombinant Mycobacterium strains with improved vaccinal properties for use as vaccinating agents are provided. The parent strains of the recombinant Mycobacteriumstrains are selected for their potent immunogenicity. The Mycobacteriumstrains do not display antibiotic resistance, and do not exhibit horizontal transfer to gram-negative bacteria. |
申请公布号 |
WO2006060332(A2) |
申请公布日期 |
2006.06.08 |
申请号 |
WO2005US42976 |
申请日期 |
2005.11.29 |
申请人 |
AERAS GLOBAL TB VACCINE FOUNDATION |
发明人 |
SUN, RONGGAI;HONE, DAVID, MICHAEL;SADOFF, JERALD, C |
分类号 |
A61K39/02;A61K39/04;C12N1/21 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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