The present invention relates to a method for producing derivatives of wild-type protein allergens with reduced allergenic activity, characterized in by the following steps: providing a wild-type protein allergen with an allergenic activity, splicing said wild-type protein allergen into two parts, said two parts having a reduced allergenic activity or lacking allergenic activity and rejoining said two fragments in inverse orientation; as well as allergen derivatives.
申请公布号
WO2006058359(A2)
申请公布日期
2006.06.08
申请号
WO2005AT00486
申请日期
2005.12.02
申请人
"BIOMAY" PRODUKTIONS- UND HANDELS- AKTIENGESELLSCHAFT;WESTRITSCHNIG, KERSTIN;FOCKE, MARGARETE;VALENT, PETER;KELLER, WALTER;VALENTA, RUDOLF
发明人
WESTRITSCHNIG, KERSTIN;FOCKE, MARGARETE;VALENT, PETER;KELLER, WALTER;VALENTA, RUDOLF