发明名称 PYRIDOXAL-5´-PHOSPHATE AND RELATED COMPOUNDS IN COMBINATION WITH THERAPEUTIC CADIOVASCULAR COMPOUNDS FOR TREATING ANGINA.
摘要 <p>Methods for treating angina are described. A method. for treating angina is directed to concurrently administering a compound with a therapeutic cardiovascular compound. The combination therapy described employs suitable therapeutic cardiovascular compounds, such as an a calcium channel blocker, a ß-adrenergic blocker, nitrates, partial fatty acid oxidation inhibitors, potassium channel activators, or a mixture thereof, in combination with a compound such as pyridoxal-5'­phosphate, pyridoxic acid, pyridoxal, pyridoxine, pyridoxamine, 3-acylated analogues of pyridoxal, 3-acylated analogues of pyridoxal-4,5-aminal, pyridoxine phosphonate analogues, a pharmaceutically acceptable acid addition salt thereof, or a mixture thereof. The invention also includes a novel composition comprising at least one compound and nitrates, partial fatty acid oxidation inhibitors, potassium channel activators, calcium channel blockers, ß-adrenergic blockers, or a mixture thereof.</p>
申请公布号 WO2006058411(A1) 申请公布日期 2006.06.08
申请号 WO2005CA01470 申请日期 2005.09.26
申请人 MEDICURE INTERNATIONAL INC.;FRIESEN, ALBERT 发明人 FRIESEN, ALBERT
分类号 A61K31/675;A61K31/138;A61K31/277;A61K31/34;A61K31/44;A61K31/4406;A61K31/4415;A61K31/496;A61P9/10 主分类号 A61K31/675
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