| 摘要 |
<P>PROBLEM TO BE SOLVED: To obtain an immunotherapeutic agent effective for treatment and prevention of metastasis and recurrence of malignant tumors of hematopoietic organs such as multiple myeloma, leukemia, malignant lymphoma, etc., and solid cancers such as lung cancer, breast cancer, etc., and to provide an immunotherapy using the preparation. <P>SOLUTION: The synthetic peptide is derived from human myeloma HM1.24 protein. The antigen has the peptide. The DNA molecule encodes the peptide. The dendritic cells are sensitized with the peptide or the antigen presenting cells are derived from the antigen. The cytotoxic T lymphocyte is derived from the peptide. The immunotherapeutic agent is excellently effective for treatment and prevention of metastasis and recurrence of malignant tumors of hematopoietic organs such as multiple myeloma, leukemia, malignant lymphoma, etc., and solid cancers such as lung cancer, breast cancer, etc., and is safe. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
