Compounds, compositions and methods are provided for modulating the expression of HIF 1-beta. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1-beta. Methods of using these compounds for modulation of HIF1-beta expression and for diagnosis and treatment of diseases and conditions associated with expression of HIFI-beta are provided.
申请公布号
WO2006026485(A3)
申请公布日期
2006.06.08
申请号
WO2005US30513
申请日期
2005.08.25
申请人
ISIS PHARMACEUTICALS, INC.;MARCUSSON, ERIC, G.;HENRY, SCOTT;KIM, YOUNGSOO;DOBIE, KENNETH, W.
发明人
MARCUSSON, ERIC, G.;HENRY, SCOTT;KIM, YOUNGSOO;DOBIE, KENNETH, W.
