| 摘要 |
Processes for preparing bis(urea-urethane) compounds wherein R<SUB>1 </SUB>is alkyl, aryl, arylalkyl, or alkylaryl, R<SUB>2 </SUB>is alkylene, arylene, arylalkylene, or alkylarylene, R<SUB>3 </SUB>is alkylene, arylene, arylalkylene, or alkylarylene, and R<SUB>4 </SUB>is hydrogen or alkyl, comprising: (1) first bring to a reaction temperature of about 20-125° C. a reaction mixture comprising monoalcohol reactant R<SUB>1</SUB>-OH and diisocyanate reactant OCN-R<SUB>2</SUB>-NCO, the monoalcohol being present in an amount of about 0.8-1.2 moles monoalcohol per mole diisocyanate, the monoalcohol and diisocyanate reactants being admixed in a solvent, the reactants and solvent being present in relative amounts of at least about 1 milliliter solvent per millimole diisocyanate, the reaction temperature continuing until reaction between the monoalcohol and the diisocyanate is complete; and (2) subsequent to step (1), adding to the reaction mixture diamine without isolating the reaction product of step (1), thereby forming compound of the formula in desirably high yield and purity.
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