OPTIMIZED BACTERIAL HOST STRAINS OF METHYLOMONAS SP.16A
摘要
Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 andcrtN3 genes of the carotenoid biosynthetic pathway. The resulting strains lack pigmented C<SUB>30</SUB> carotenoid compounds, and show an increase in the production of C<SUB>40</SUB> carotenoids. The use of the optimized host strains for the production of the C<SUB>40</SUB> carotenoids canthaxanthin and astaxanthin is also described.
申请公布号
WO2005072086(A3)
申请公布日期
2006.06.08
申请号
WO2004US40622
申请日期
2004.12.02
申请人
E.I. DUPONT DE NEMOURS AND COMPANY;SHARPE, PAMELA, L.;CHENG, QIONG;BOSAK, MELISSA, D.;TAO, LUAN;SEDKOVA, NATALIA