Agent, useful for oxidative coloring of keratin fibers e.g. fur and wool and as hair dye, comprises nonionic azomethine compounds e.g. 4-((3-pyridinylmethylidene)amino)phenol

摘要

Agent (A), for oxidative coloring of keratin fibers, comprises nonionic azomethine compounds (I). Agent (A), for oxidative coloring of keratin fibers, comprises nonionic azomethine compounds of formula (I). Either R1, R2 : H, aliphatic or (hetero)aromatic group (optionally substituted with amino, OH, nitrile, alkoxy, alkylsulfonyl or keto); or CR1R2 : optionally saturated (hetero)cyclic compound; either R3 : OH, amino, 1-8C alkylamino, 2-16C dialkylamino, hydroxyethylamino, 2,3-dihydroxypropylamino, di(2-hydroxyethyl)amino, di(2-hydroxypropyl)amino, di(2-methoxyethyl)amino, dimethylaminoethylamino, N-(1-4C)alkyl-N-(2-dimethylaminoethyl), (3-6C)alkoxy alkylamino, N-(1-4C)alkyl-N-(2-hydroxyethyl), morpholino, pyrrolidino (optionally substituted with 1-2 OH, methoxymethyl, pyridyl, carbonamide or hydroxymethyl), piperidino (optionally substituted with amino, CH3, ethyl, aminomethyl, phenyl or benzyl), piperazino (optionally substituted with carbon backbone bound amino-ethyl or 1-2 carbon back bone bound CH3), N'-phenyl-piperazino, N'-benzyl-piperazino, N'-methyl-piperazino, N'-(2-hydroxyethyl)-piperazino or N'-(2-pyrimidyl)-piperazino; and R4 : H, 1-8C alkyl (optionally substituted with halo), 1-8C alkoxy, 1-8C alkoxyalkyl, 1-3C hydroxyalkyl, 2-3C dihydroxyalkyl, Cl, F, CF3, nitrile, methoxymethyl, 1-3C alkyl aminomethyl, hydroxy ethylaminomethyl, dimethylaminomethyl, pyrrolidinylmethyl, morpholinomethyl, furyl, pyrrolyl, thiazolyl, naphthyl, fluorenyl, quinolinyl, isoquinolinyl, nicotinoyl, acetylaminomethyl, cyanoethyl, pyrimidinyl, acrylamide (optionally containing amide nitrogen, 1-4C-alkyl, cyclopropyl, allyl, 3-5C alkoxyalkyl, 3-5C dihydroxyalkyl, morpholinoethyl, furylmethyl, tetrahydro furylmethyl, imidazolyl-2-3C-alkyl or 1-4C-hydroxy-alkyl), acrylamide in the amide nitrogen portion of the ring system, acryl anilide (optionally phenyl ring substituted with OH, halo, nitro or hydroxyethoxy), phenyl (optionally substituted with nitro, OCH3, carbonamide, formyl, acetyl, hydroxyethyl, hydroxyethoxy, cyanomethyl, methylthio, halo, CF3, nitrile, 1-6C-alkyl, OH, phenoxy or phenyl), pyridinyl (optionally substituted with 1-2 CH3, carbonamide, CF3 or nitro) or thienyl (optionally substituted with halo, nitro, formyl, hydroxyethylaminomethyl, dimethylamino ethylaminomethyl, morpholinomethyl, pyrrolidinylmethyl, phenylaminomethyl, hydroxymethyl or methyl); or R3+R4 : forms bridge (when arranged in ortho position); and Y1 : CH or N. R2 is not H, when Y1 is CH and R1 is an aromatic six ring substituted with 2-3 OH. [Image].