发明名称 Antibacterial oxazolidinones
摘要 A compound of the formula (I), or a pharmaceutically-acceptable salt, or in-vivo hydrolysable ester thereof: formula (I) wherein C is selected from D and E, formula (II) R<SUB>2</SUB>a, R<SUB>6</SUB>a, and R<SUB>3</SUB>a are independently selected from for example H, CF<SUB>3</SUB>, Me and Et; R<SUB>2</SUB>b and R<SUB>6</SUB>b are independently selected from for example H, F, CF<SUB>3</SUB>, Me and Et; R<SUB>1</SUB>b is -NRz-Z wherein Rz is for example hydrogen and Z is a 5- or 6-membered heteroaryl ring; R<SUB>4 </SUB>is for example an optionally substituted 5- or 6-membered heterocyclic ring system. Methods for making compounds of the formula (I), compositions containing them and their use as antibacterial agents are also described.
申请公布号 US2006116389(A1) 申请公布日期 2006.06.01
申请号 US20050539484 申请日期 2005.06.17
申请人 ASTRA ZENECA AB 发明人 GRAVESTOCK MICHAEL B.;HALES NEIL J.;TURNER PAUL
分类号 A61K31/513;A61K31/4439;A61K31/506;A61K31/655;A61P31/04;C07D413/02;C07D413/14;C07D417/14 主分类号 A61K31/513
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