SULFATED MOLECULAR UMBRELLAS CONTAINING 6-200 CHOLANIC ACID (DERIVATIVE) UNITS AS ANTI-HIV AND ANTI-HSV AGENTS
摘要
A chemical genus of sulfated cholestanes attached to an oligomer through amide or ester bonds is disclosed. The compounds are useful as anti human immunodeficiency virus (HIV) and anti-herpes simplex virus (HSV) agents. The compounds have the general formula n, in which CPS (the structure within the square brackets) is a cholamic acid derivative. R<SUP>1</SUP> to R<SUP>16</SUP> are chosen independently from H, OH and OSO<SUB>3</SUB>
申请公布号
WO2006034369(A3)
申请公布日期
2006.06.01
申请号
WO2005US33880
申请日期
2005.09.20
申请人
LEHIGH UNIVERSITY;ITY MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERS;REGEN, STEVEN;HEROLD, BETSY, C.