发明名称 |
COMPOSICIONES FARMACEUTICAS Y SU UTILIZACION, ESPECIALMENTE PARA EL TRATAMIENTO DE ENFERMEDADES NEURODEGENERATIVAS. |
摘要 |
Use of a cpd. (A) that at least partly inhibits the activity of p53 protein to prepare a compsn. for treating and/or preventing neurodegenerative diseases is new. Also claimed is recombinant virus contg., inserted in its genome, nucleic acid (a) encoding a mutated form of p53 able to antagonise p53 activity; (b) contg. all or part of the p53 binding site and/or (c) encoding antisense material able to reduce p53 expression at translational or transcriptional levels.
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申请公布号 |
ES2253739(T3) |
申请公布日期 |
2006.06.01 |
申请号 |
ES19940928933T |
申请日期 |
1994.09.29 |
申请人 |
AVENTIS PHARMA S.A. |
发明人 |
MALLET, JACQUES;REVAH, FREDERIC;STUTZMANN, JEAN-MARIE |
分类号 |
C12N15/09;A61K31/70;A61K31/713;A61K38/00;A61K48/00;A61P25/00;A61P25/08;A61P25/28;A61P43/00;C07K14/82;C12N7/00;C12N7/01;C12N15/113;C12N15/86;C12N15/861;(IPC1-7):C12N15/11 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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