发明名称 |
Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient |
摘要 |
(R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetic acid anilide or its salt shows a potent bladder relaxation effect in "isolated rat bladder smooth muscle relaxation test", dose-dependently lowers the contraction frequency of rhythmic bladder contractions in "rat rhythmic bladder contraction measurement test" and, moreover, prolongs the urination intervals in "urination functions measurement test on cyclophosphamide-induced overactive bladder model rat". Owing to these effects, the above compound is useful as a remedy for ovaractive bladder.
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申请公布号 |
US2006115540(A1) |
申请公布日期 |
2006.06.01 |
申请号 |
US20050534290 |
申请日期 |
2005.05.09 |
申请人 |
TAKASU TOSHIYUKI;SATO SHUICHI;UKAI MASASHI;MARUYAMA TATSUYA |
发明人 |
TAKASU TOSHIYUKI;SATO SHUICHI;UKAI MASASHI;MARUYAMA TATSUYA |
分类号 |
A61K33/00;A61K31/426;A61P13/00;A61P13/10;C07D277/40 |
主分类号 |
A61K33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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