发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING A SOLID DISPERSION WITH A POLYMER MATRIX CONTAINING A CONTINUOUS POLYDEXTROSE PHASE AND A CONTINUOUS PHASE OF A POLYMER OTHER THAN POLYDEXTROSE |
摘要 |
The invention relates to a solid pharmaceutical composition comprising a solid dispersion containing at least one active principle and a pharmaceutically-acceptable polymer matrix. The invention is characterised in that the pharmaceutically-acceptable polymer matrix comprises a mixture of (i) polydextrose, in the form of a continuous polydextrose phase, in order to favour the disintegration of the composition in an aqueous medium and (ii) at least one polymer other than polydextrose, in the form of a continuous phase, whereby the polydextrose is in a concentration of at least 20 wt.- % and the at least one polymer other than polydextrose is in a concentration of at least 20 wt.- % in relation to the total weight of the pharmaceutically-acceptable polymer matrix. |
申请公布号 |
WO2006032762(A3) |
申请公布日期 |
2006.06.01 |
申请号 |
WO2005FR02288 |
申请日期 |
2005.09.15 |
申请人 |
SANOFI-AVENTIS;BEDOS, MICHEL;BREUL, THIERRY;BYARD, STEPHEN;RIBEIRO DOS SANTOS, ISABEL |
发明人 |
BEDOS, MICHEL;BREUL, THIERRY;BYARD, STEPHEN;RIBEIRO DOS SANTOS, ISABEL |
分类号 |
A61K9/10;A61K9/20;A61K47/36 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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