发明名称 |
Method to provide bacterial ghosts with antigens |
摘要 |
Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain, homolog or functional derivative thereof. The method includes treating the cell-wall material with a solution capable of removing a cell-wall component such as a protein, lipoteichoic acid or carbohydrate from the cell-wall material and contacting the proteinaceous substance with the cell-wall material.
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申请公布号 |
US2006115491(A1) |
申请公布日期 |
2006.06.01 |
申请号 |
US20050299304 |
申请日期 |
2005.12.09 |
申请人 |
LEENHOUTS CORNELIS J;RAMASAMY RANJAN;STEEN ANTON;KOK JAN;BUIST GIRBE;KUIPERS OSCAR P |
发明人 |
LEENHOUTS CORNELIS J.;RAMASAMY RANJAN;STEEN ANTON;KOK JAN;BUIST GIRBE;KUIPERS OSCAR P. |
分类号 |
A61K39/02;A61K38/00;A61K39/015;C07K14/335;C07K19/00;C12N1/00;C12N15/31;C12N15/63 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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