发明名称 METHODS RELATED TO THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY CONDITIONS
摘要 The invention includes methods of neuroprotection, inducing release of neurotrophic factors, inhibiting the over-activation of innate immune cells, attenuating the toxin-induced death and/or damage of tissues, reducing inflammation, treating an inflammation-related condition, and inhibiting NADPH oxidase, that includes contacting or administering an effective amount of at least one compound of the invention that include: valproic acid, sodium butyrate, and salts thereof; opioid peptides; a peptide comprising the tripeptide GGF; and morphinans, such as naloxone, naltrexone, 3-hydroxy-morphinan and dextromethorphan.
申请公布号 WO2005112931(A3) 申请公布日期 2006.06.01
申请号 WO2005US16691 申请日期 2005.05.12
申请人 SERVICES BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED;HONG, JAU-SHYONG;QIN, LIYA;LI, GUORONG;BLOCK, MICHELLE;ZHANG, WEI;CHEN, PO-SEE;PENG, GIIA-SHUEN 发明人 HONG, JAU-SHYONG;QIN, LIYA;LI, GUORONG;BLOCK, MICHELLE;ZHANG, WEI;CHEN, PO-SEE;PENG, GIIA-SHUEN
分类号 A61K31/485;A61K38/00;A61K38/06;A61K38/33;A61P29/00 主分类号 A61K31/485
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