发明名称 |
NOVEL LACTOBACILLUS, LIVING BODY ACTIVATING LACTOBACILLUS PREPARATION AND PREVENTIVE OR THERAPEUTIC AGENT AGAINST LIVING BODY INFECTION |
摘要 |
There has been effort to develop a lactobacillus that would be useful as a probiotic, and to develop a lactobacillus which would colonize and proliferate in lesions of infection, eliminating the causal bacteria. This problem was resolved by developing a Lactobacillus casei species having the following key properties. (1) The species can be grown in the presence of any of one to four amino acids as a nitrogen source necessary for growth. (2) When a growth-promoting culture medium is inoculated with the species and Escherichia coli in the same count and subjected to anaerobic mixed culturing at 37°C, the final count of lactobacilli is 50% or more of the coliform count. (3) Upon cultivation in an appropriate culture medium, the final pH value is 4.0 or below, and the highest acidity is 1.5% or more. (4) The species is resistant to 5% bile salts. (5) The species produces an antibiotic.
|
申请公布号 |
EP1661982(A1) |
申请公布日期 |
2006.05.31 |
申请号 |
EP20040770950 |
申请日期 |
2004.07.27 |
申请人 |
BHPH COMPANY LIMITED |
发明人 |
HATA, TADAYO;TOSHIMORI, HITOSHI;MARUOKA, TOSHIYUKI |
分类号 |
A61K35/74;A61P31/04;C12R1/245;(IPC1-7):C12N1/20;A01N63/02 |
主分类号 |
A61K35/74 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|