摘要 |
Compounds of Formula I, wherein R<SUB>1</SUB>-R<SUB>8 </SUB>are defined herein are provided, together with pharmaceutically acceptable salts, hydrates, metabolites, and/or prodrugs thereof. Uses of these compounds for inhibiting beta amyloid production and for the prevention and treatment of Alzheimer's Disease and Down's syndrome are described. |
申请人 |
WYETH ARQULE INC |
发明人 |
KREFT, ANTHONY, F.;COLE, DEREK, C.;WOLLER, KEVIN, R.;STOCK, JOSEPH, R.;KUTTERER, KRISTINA, M.;KUBRAK, DENNIS, M.;MANN, CHARLES, W.;MOORE, WILLIAM, J. N;CASEBIER, DAVID, S. |