Recombinant expression vectors encoding the L1 and L2 proteins of papillomavirus, methods of making and using the recombinant proteins and purified virus-like particles comprised of the recombinant proteins are provided.
申请公布号
EP0757717(B1)
申请公布日期
2006.05.31
申请号
EP19950919820
申请日期
1995.05.15
申请人
MERCK & CO., INC.
发明人
JANSEN, KATHRIN U.;COOK, JAMES C., III;GEORGE, HUGH A.;HOFMANN, KATHRYN J.;JOYCE, JOSEPH G.;LEHMAN, ERNEST DALE;MARKUS, HENRY Z.;ROSOLOWSKY, MARK;SCHULTZ, LOREN D.