| 摘要 |
<p>wherein R1 is 5-methylpyridin-2-yl, p-tolyl, or mesityl; and R2 is any of the general formulae (II) to (IX): (wherein R3 is C1-4 alkyl; R4 is hydrogen or C1-4 alkyl; R5 is hydrogen, 3-pyridylmethyl, or 4-pyridylmethyl; and R6 is 2,4 -dihydroxybenzyl, 3-pyridylmethyl, or 4-pyridylmethyl) or R2 is the formula (X) when R1 is mesityl; (X) or a pharmaceutically acceptable salt of the compound. The compound is effective in preventing itches and is useful for the prevention of or treatments for: reactions on insect's bites, reactions on environmental allergens, skin infections, external vermination, or itches occurring in renal dialysis patients.</p> |
