| 发明名称 |
Parazoles and methods of making and using the same |
| 摘要 |
The invention is based on the discovery that compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I (I). |
| 申请公布号 |
ZA200506408(B) |
申请公布日期 |
2006.05.31 |
| 申请号 |
ZA20050006408 |
申请日期 |
2005.08.11 |
| 申请人 |
BIOGEN IDEC MA INC |
发明人 |
WEN-CHERNG LEE;FENG SHAN;MARK CORNEBISE;MARYBETH CARTER;BORIACK-SJODIN, PAULA, A.;PETER, RUSSEL, C.;LIHONG SUN;CLAUDIA CHUAQUI;PONTZ, TIMOTHY, W.;JUSWINDER SINGH;LEONA LING |
| 分类号 |
A01N;A01N43/40;A01N43/42;A01N43/58;A01N43/60;A61K;A61K31/44;A61K31/4427;A61K31/47;A61K31/495;A61K31/4965;A61K31/497;A61K31/50;A61K31/501;A61K31/54;A61P35/00;C07D;C07D401/04;C07D401/14;C07D405/14;C07D407/14;C07D413/14;C07D471/04 |
主分类号 |
A01N |
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