发明名称 INHIBITORS OF SERINE PROTEASE ACTIVITY AND THEIR USE IN METHODS AND COMPOSITIONS FOR TREATMENT OF BACTERIAL INFECTIONS
摘要 <p>A novel method of treating and preventing bacterial diseases is provided. In particular, the present invention relates to compositions and methods for inhibition of Gram negative, Gram positive and acid fast bacilli in general and tuberculosis (TB), mycobacterium avium complex (MAC), and anthrax in particular. Thus, the invention relates to modulation of cellular activities, including macrophage activity, and the like. More particularly, the present invention relates to the inhibitory compounds comprising naturally occurring and man-made inhibitors of serine protease.</p>
申请公布号 EP1660094(A2) 申请公布日期 2006.05.31
申请号 EP20040801916 申请日期 2004.08.26
申请人 THE REGENTS OF THE UNIVERSITY OF COLORADO 发明人 SHAPIRO, LELAND
分类号 A61K31/519;A61K38/48;A61K38/57;A61K39/395;C12N;C12N9/64;(IPC1-7):A61K31/519 主分类号 A61K31/519
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