发明名称 |
Process for the preparation of optically pure or enriched racemic tetralone |
摘要 |
A process for producing substantially optically pure sertraline utilizes chromatographic separation on a solid stationary chiral phase of spherical clay particles having an interlayer containing an optically pure metal-organic complex, and a liquid mobile phase preferably containing at least methyl acetate. The liquid mobile phase is preferably free of acetonitrile. The process is operable at temperatures above 40° C. |
申请公布号 |
ZA200402652(B) |
申请公布日期 |
2006.05.31 |
申请号 |
ZA20040002652 |
申请日期 |
2004.04.05 |
申请人 |
PFIZER PRODUCTS INC |
发明人 |
LAURENT BERGER;RAPHAEL DUVAL;PHILIPPE TAILLASSON;INGO WEBER;ALEXANDER WICK |
分类号 |
C07B57/00;C07B63/00;C07C;C07C45/78;C07C45/79;C07C49/687 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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