发明名称 N3 ALKYLATED BENZIMIDAZOLE DERIVATIVES AS MEK INHIBITORS.
摘要 <p>Disclosed are compounds of the formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein W, R1, R2, R7, R8, R9, and R10 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative diseases in mammals, and pharmaceutical compositions containing such compounds.</p>
申请公布号 MXPA06002268(A) 申请公布日期 2006.05.31
申请号 MX2006PA02268 申请日期 2004.08.20
申请人 ARRAY BIOPHARMA, INC. 发明人 KEVIN KOCH
分类号 A61K31/4184;C07D235/06;C07D235/08;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/12;C07D405/06;C07D413/04;C07D413/06;C07D417/06;C07D417/12;C07F9/6506;C07F9/6558;(IPC1-7):A61K31/418 主分类号 A61K31/4184
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