发明名称 |
Sulfur analogues of 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) for treating excess of glucocorticoids |
摘要 |
The present invention is related to novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues, their use as antiglucocorticoids for the treatment and/or prophylaxis of disease associated to an excess of glucocorticoids. In particular, the invention relates to the use of novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues for treating Cushing's syndrome, iatrogenic hypercortisolism or depression. Also the present invention is related to methods of preparing the novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues.
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申请公布号 |
US7053228(B2) |
申请公布日期 |
2006.05.30 |
申请号 |
US20030363860 |
申请日期 |
2003.08.20 |
申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. |
发明人 |
BURTON GERARDO;LANTOS CARLOS P.;VELEIRO ADRIANA SILVIA |
分类号 |
A61K31/58;C07J1/00;A61K31/56;A61P5/46;A61P13/12;A61P25/24;A61P37/02;A61P37/04;A61P37/06;C07D333/02;C07D333/50;C07J53/00;C07J71/00 |
主分类号 |
A61K31/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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