发明名称 |
METHODS OF DEVELOPING A STEM CELL LINE |
摘要 |
<p>The invention relates to a methodology for creating an embryonic stem cell line. The stem cells derived from the invention are of substantially better quality of human stem cells currently known to exist. The inventors have discovered inter alia, that when the chromosome complement of a first polar body (PB-I) is normal, it alone is in more than 80% of cases sufficient to predict that an embryo which has developed from an oocyte associated with the PB-I is also euploid and competent. Euploid embryos ensure are a key prerequisite in the making of euploid embryonic stem cells. This allows the technician minimize the number of disrupted embryos by only disrupting those embryos determined to be euploid.</p> |
申请公布号 |
WO2006055852(A1) |
申请公布日期 |
2006.05.26 |
申请号 |
WO2005US42015 |
申请日期 |
2005.11.17 |
申请人 |
MOSAIC REPRODUCTIVE HEALTH AND GENETICS, LLC;SHER, GEOFFREY;KESKINTEPE, LEVENT |
发明人 |
SHER, GEOFFREY;KESKINTEPE, LEVENT |
分类号 |
C12N5/0735;C12N15/873;C12N15/877;C12Q1/68;G01N33/50 |
主分类号 |
C12N5/0735 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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