摘要 |
Disclosed herein is a class of pyrazolo[1,5-a]pyrimidine compounds of formula (I) as inhibitors of cyclin dependent kinases (CDKs), methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions, wherein the substituents for the variables shown in formula (I) are as defined in the specification.
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申请人 |
SCHERING CORPORATION;PHARMACOPEIA DRUG DISCOVERY, INC |
发明人 |
GUZI, TIMOTHY J;PARUCH, KAMIL;DWYER, MICHAEL P;DOLL, RONALD J;ALVAREZ, CARMEN;CHAN, TIN-YAU;KNUTSON, CHAD;MADISON, VINCENT;FISCHMANN, THIERRY O;DILLARD, LAWRENCE W;TRAN, VINH D;HE, ZHEN MIN;JAMES, RAY ANTHONY;PARK, HAENGSOON;GIRIJAVALLABHAN, VIYYOOR MOOPIL |