发明名称 PYRIDINE DERIVATIVES FOR INHIBITING HUMAN STEAROYL-COA-DESATURASE
摘要 Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where x, y, G, J, K, L, M, W, V, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>5</SUP>a, R<SUP>6</SUP>, R<SUP>6</SUP>a, R<SUP>7</SUP>, R<SUP>7</SUP>a, R<SUP>8</SUP> and R<SUP>8</SUP>a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
申请公布号 WO2006034446(A3) 申请公布日期 2006.05.26
申请号 WO2005US34136 申请日期 2005.09.20
申请人 XENON PHARMACEUTICALS INC.;ROTH, CAROL J.;KAMBOJ, RAJENDER;KODUMURU, VISHNUMURTHY 发明人 KAMBOJ, RAJENDER;KODUMURU, VISHNUMURTHY
分类号 A61K31/496;A61P3/06;A61P3/10;A61P43/00;C07D295/18 主分类号 A61K31/496
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