摘要 |
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I), where x, y, G, J, K, L, M, W, V, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>5</SUP>a, R<SUP>6</SUP>, R<SUP>6</SUP>a, R<SUP>7</SUP>, R<SUP>7</SUP>a, R<SUP>8</SUP> and R<SUP>8</SUP>a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed. |
申请人 |
XENON PHARMACEUTICALS INC.;ROTH, CAROL J.;KAMBOJ, RAJENDER;KODUMURU, VISHNUMURTHY |
发明人 |
KAMBOJ, RAJENDER;KODUMURU, VISHNUMURTHY |