摘要 |
The invention relates, in part, to methods and compositions for the intracellular delivery of polysaccharides. In particular, the methods and compositions relate to the intracellular delivery of glycosaminoglycans, such as heparin. The invention in other aspects relates to the use of glycosaminoglycans for the treatment of proliferative disorders, such as cancer. The invention is still other aspects relates to improving cell viability. The invention also relates to the delivery of polysaccharides while avoiding unwanted effects of the polysaccharides. For example, heparin can be delivered while avoiding its anticoagulant effects. |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;BERRY, DAVID, A.;ANDERSON, DANIEL, G.;LYNN, DAVID, M.;SASISEKHARAN, RAM;LANGER, ROBERT, S. |
发明人 |
BERRY, DAVID, A.;ANDERSON, DANIEL, G.;LYNN, DAVID, M.;SASISEKHARAN, RAM;LANGER, ROBERT, S. |